Evidence used
- No CISA KEV confirmation is currently recorded.
- The selected CVSS metric records a network-reachable, unauthenticated path with no user interaction.
- EPSS is 0.59% for the current model date.
BlackTreeCVE Intelligencesamtools · htslib
Official source article: GitHub GHSA-XXMP-V7H3-GPWP ↗. Check the applicable product and release in the original source.
High technical severity; prioritise exposed affected systems while verifying vendor guidance. Verified remediation exists for at least one product or source, but 4 structured product or package states remain unresolved. Apply remediation only to the exact product branch confirmed by its source.
Verified remediation exists for at least one product or source, but 4 structured product or package states remain unresolved. Apply remediation only to the exact product branch confirmed by its source.
Debian, ubuntu findings are scoped to the named distribution, release and source package. An absent finding does not mean a package is unaffected.
BlackTree has verified remediation for at least one product or source, but the relevant distribution still reports no fixed package for 4 affected package states shown here. Treat those rows as affected with no fix until that distribution publishes a fixed version.
A published vendor fix does not prove that a matching update is enabled and installable on a particular asset. Confirm the local package candidate before scheduling remediation.
| Distribution release | Source package | Vendor state | Fixed version | Evidence |
|---|---|---|---|---|
| Debian trixietrixie · source | htslib | Affected, no fix publishedDebian currently tracks this release as open. | Not published in this feed | Debian Security Tracker ↗Source updated 5 Oct 2026 |
| Debian bookwormbookworm · source | htslib | Affected, no fix publishedDebian currently tracks this release as open. | Not published in this feed | Debian Security Tracker ↗Source updated 5 Oct 2026 |
| Debian forkyforky · source | htslib | Affected, no fix publishedDebian currently tracks this release as open. | Not published in this feed | Debian Security Tracker ↗Source updated 5 Oct 2026 |
| Debian sidsid · source | htslib | Affected, no fix publishedDebian currently tracks this release as open. | Not published in this feed | Debian Security Tracker ↗Source updated 5 Oct 2026 |
| Ubuntu 24.04 LTSnoble · standard archive | htslib | Under evaluationCanonical reports that the package might be affected and still needs evaluation or fixing. | Not published in this feed | Canonical Ubuntu Security ↗Source updated 5 Oct 2026 |
High technical severity; prioritise exposed affected systems while verifying vendor guidance. Verified remediation exists for at least one product or source, but 4 structured product or package states remain unresolved. Apply remediation only to the exact product branch confirmed by its source.
Fix availability varies by productHTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. While most alignment records store DNA sequence and quality values, the format also allows them to omit this data in certain cases to save space. Due to some quirks of the CRAM format, it is necessary to handle these records carefully as they will actually store data that needs to be consumed and then discarded. Unfortunately the `cram_decode_seq()` did not handle this correctly in some cases. Where this happened it could result in reading a single byte from beyond the end of a heap allocation, followed by writing a single attacker-controlled byte to the same location. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. While most alignment records store DNA sequence and quality values, the format also allows them to omit this data in certain cases to save space. Due to some quirks of the CRAM format, it is necessary to handle these records carefully as they will actually store data that needs to be consumed and then discarded. Unfortunately the `cram_decode_seq()` did not handle this correctly in some cases. Where this happened it could result in reading a single byte from beyond the end of a heap allocation, followed by writing a single attacker-controlled byte to the same location. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
A heap overflow condition is a buffer overflow, where the buffer that can be overwritten is allocated in the heap portion of memory, generally meaning that the buffer was allocated using a routine such as malloc().
An attacker operating through a network path may attempt exploitation without authentication or user interaction. If successful, the issue may execute code or commands in the affected security context.
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. While most alignment records store DNA sequence and quality values, the format also allows them to omit this data in certain cases to save space. Due to some quirks of the CRAM format, it is necessary to handle these records carefully as they will actually store data that needs to be consumed and then discarded. Unfortunately the `cram_decode_seq()` did not handle this correctly in some cases. Where this happened it could result in reading a single byte from beyond the end of a heap allocation, followed by writing a single attacker-controlled byte to the same location. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
A heap overflow condition is a buffer overflow, where the buffer that can be overwritten is allocated in the heap portion of memory, generally meaning that the buffer was allocated using a routine such as malloc().
An attacker operating through a network path may attempt exploitation without authentication or user interaction. If successful, the issue may execute code or commands in the affected security context.
CVSS severity, EPSS forecast probability, public exploit material and CISA-confirmed exploitation are separate signals.
No CISA KEV match was present at the last successful refresh. This means no confirmation from that source, not proof of no exploitation.
No exploit-tagged reference or CISA SSVC proof-of-concept state is currently recorded. Research may still exist outside the structured feeds.
CWE-122: Heap-based Buffer Overflow. A heap overflow condition is a buffer overflow, where the buffer that can be overwritten is allocated in the heap portion of memory, generally meaning that the buffer was allocated using a routine such as malloc().
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:H/VA:L/SC:N/SI:N/SA:NCommon Vulnerability Scoring System 4.0: the compact vector below is decoded into plain language.
Operational remediation based on structured source evidence.
Published 18 Mar 2026 · Last source change 18 Mar 2026, 18:37 UTC · CWE-122 · Heap-based Buffer Overflow
Core structured fields are present and their contributing authorities are shown above.
No material field changes have been recorded since change tracking began. Routine source refreshes and cosmetic edits are intentionally excluded.